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Synthesis and bioevaluation of [(18)F]4-fluoro-m-hydroxyphenethylguanidine ([(18)F]4F-MHPG): a novel radiotracer for quantitative PET studies of cardiac sympathetic innervation
A new cardiac sympathetic nerve imaging agent, [(18)F]4-fluoro-m-hydroxyphenethylguanidine ([(18)F]4F-MHPG), was synthesized and evaluated. The radiosynthetic intermediate [(18)F]4-fluoro-m-tyramine ([(18)F]4F-MTA) was prepared and then sequentially reacted with cyanogen bromide and NH(4)Br/NH(4)OH...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2013
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594138/ https://ncbi.nlm.nih.gov/pubmed/23416009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.01.106 |
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