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4-[(18)F]fluoro-m-hydroxyphenethylguanidine: A Radiopharmaceutical for Quantifying Regional Cardiac Sympathetic Nerve Density with Positron Emission Tomography

4-[(18)F]fluoro-m-hydroxyphenethylguanidine ([(18)F]4F-MHPG, [(18)F]1) is a new cardiac sympathetic nerve radiotracer with kinetic properties favorable for quantifying regional nerve density with PET and tracer kinetic analysis. An automated synthesis of [(18)F]1 was developed in which the intermedi...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Jang, Keun Sam, Jung, Yong-Woon, Gu, Guie, Koeppe, Robert A., Sherman, Phillip S., Quesada, Carole A., Raffel, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520396/
https://ncbi.nlm.nih.gov/pubmed/23965035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400770g
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