The Natural Agonist of Estrogen Receptor β Silibinin Plays an Immunosuppressive Role Representing a Potential Therapeutic Tool in Rheumatoid Arthritis

Estrogens, in particular 17β-estradiol (E2), have a strong influence on the immune system and also affect pathological conditions such as autoimmune diseases. The biological effects of E2 are mediated by two intracellular receptors, i.e., estrogen receptor (ER)α and ERβ, which function as ligand-act...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Dupuis, Maria Luisa, Conti, Fabrizio, Maselli, Angela, Pagano, Maria Teresa, Ruggieri, Anna, Anticoli, Simona, Fragale, Alessandra, Gabriele, Lucia, Gagliardi, Maria Cristina, Sanchez, Massimo, Ceccarelli, Fulvia, Alessandri, Cristiano, Valesini, Guido, Ortona, Elena, Pierdominici, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107853/
https://ncbi.nlm.nih.gov/pubmed/30174672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01903
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