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Loss of GCNT2/I-branched glycans enhances melanoma growth and survival

Cancer cells often display altered cell-surface glycans compared to their nontransformed counterparts. However, functional contributions of glycans to cancer initiation and progression remain poorly understood. Here, from expression-based analyses across cancer lineages, we found that melanomas exhi...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Sweeney, Jenna Geddes, Liang, Jennifer, Antonopoulos, Aristotelis, Giovannone, Nicholas, Kang, Shuli, Mondala, Tony S., Head, Steven R., King, Sandra L., Tani, Yoshihiko, Brackett, Danielle, Dell, Anne, Murphy, George F., Haslam, Stuart M., Widlund, Hans R., Dimitroff, Charles J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105653/
https://ncbi.nlm.nih.gov/pubmed/30135430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05795-0
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