Loss of GCNT2/I-branched glycans enhances melanoma growth and survival

Cancer cells often display altered cell-surface glycans compared to their nontransformed counterparts. However, functional contributions of glycans to cancer initiation and progression remain poorly understood. Here, from expression-based analyses across cancer lineages, we found that melanomas exhi...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Sweeney, Jenna Geddes, Liang, Jennifer, Antonopoulos, Aristotelis, Giovannone, Nicholas, Kang, Shuli, Mondala, Tony S., Head, Steven R., King, Sandra L., Tani, Yoshihiko, Brackett, Danielle, Dell, Anne, Murphy, George F., Haslam, Stuart M., Widlund, Hans R., Dimitroff, Charles J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105653/
https://ncbi.nlm.nih.gov/pubmed/30135430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05795-0
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