Human B Cell Differentiation Is Characterized by Progressive Remodeling of O-Linked Glycans

Germinal centers (GC) are microanatomical niches where B cells proliferate, undergo antibody affinity maturation, and differentiate to long-lived memory B cells and antibody-secreting plasma cells. For decades, GC B cells have been defined by their reactivity to the plant lectin peanut agglutinin (P...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Giovannone, Nicholas, Antonopoulos, Aristotelis, Liang, Jennifer, Geddes Sweeney, Jenna, Kudelka, Matthew R., King, Sandra L., Lee, Gi Soo, Cummings, Richard D., Dell, Anne, Barthel, Steven R., Widlund, Hans R., Haslam, Stuart M., Dimitroff, Charles J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302748/
https://ncbi.nlm.nih.gov/pubmed/30619255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02857
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