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A novel cognitive disease progression model for clinical trials in autosomal-dominant Alzheimer’s disease

Clinical trial outcomes for Alzheimer’s disease are typically analyzed by using the mixed model for repeated measures (MMRM) or similar models that compare an efficacy scale change from baseline between treatment arms with or without participants’ disease stage as a covariate. The MMRM focuses on a...

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Dades bibliogràfiques
Publicat a:Stat Med
Autors principals: Wang, Guoqiao, Berry, Scott, Xiong, Chengjie, Hassenstab, Jason, Quintana, Melanie, McDade, Eric M., Delmar, Paul, Vestrucci, Matteo, Sethuraman, Gopalan, Bateman, Randall J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105413/
https://ncbi.nlm.nih.gov/pubmed/29761523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7811
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