Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas

Of nine ependymoma molecular groups detected by DNA methylation profiling, the posterior fossa type A (PFA) is most prevalent. We used DNA methylation profiling to look for further molecular heterogeneity among 675 PFA ependymomas. Two major subgroups, PFA-1 and PFA-2, and nine minor subtypes were d...

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izdano v:Acta Neuropathol
Main Authors: Pajtler, Kristian W., Wen, Ji, Sill, Martin, Lin, Tong, Orisme, Wilda, Tang, Bo, Hübner, Jens-Martin, Ramaswamy, Vijay, Jia, Sujuan, Dalton, James D., Haupfear, Kelly, Rogers, Hazel A., Punchihewa, Chandanamali, Lee, Ryan, Easton, John, Wu, Gang, Ritzmann, Timothy A., Chapman, Rebecca, Chavez, Lukas, Boop, Fredrick A., Klimo, Paul, Sabin, Noah D., Ogg, Robert, Mack, Stephen C., Freibaum, Brian D., Kim, Hong Joo, Witt, Hendrik, Jones, David T.W., Vo, Baohan, Gajjar, Amar, Pounds, Stan, Onar-Thomas, Arzu, Roussel, Martine F., Zhang, Jinghui, Taylor, J. Paul, Merchant, Thomas E., Grundy, Richard, Tatevossian, Ruth G., Taylor, Michael D., Pfister, Stefan M., Korshunov, Andrey, Kool, Marcel, Ellison, David W.
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105278/
https://ncbi.nlm.nih.gov/pubmed/29909548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1877-0
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