Patched-2 functions to limit Patched-1 deficient skin cancer growth

PURPOSE: Basal cell carcinoma (BCC) is one of the most common skin cancers, and is typically driven by an aberrantly activated Hedgehog (Hh) pathway. The Hh pathway is regulated by interactions between the Patched-1 (Ptch1) and Smoothened (Smo) receptors. Smo is an activating receptor and is subject...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Oncol (Dordr)
Hauptverfasser: Veenstra, Veronique L., Dingjan, Ilse, Waasdorp, Cynthia, Damhofer, Helene, van der Wal, Allard C., van Laarhoven, Hanneke W., Medema, Jan Paul, Bijlsma, Maarten F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2018
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105176/
https://ncbi.nlm.nih.gov/pubmed/29869097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-018-0381-9
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