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A mathematical model for the effects of amyloid beta on intracellular calcium

The accumulation of Alzheimer’s disease (AD) associated Amyloid beta (Aβ) oligomers can trigger aberrant intracellular calcium (Ca(2+)) levels by disrupting the intrinsic Ca(2+) regulatory mechanism within cells. These disruptions can cause changes in homeostasis levels that can have detrimental eff...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Latulippe, Joe, Lotito, Derek, Murby, Donovan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105003/
https://ncbi.nlm.nih.gov/pubmed/30133494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202503
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