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Connexin 43 K63-polyubiquitylation on lysines 264 and 303 regulates gap junction internalization

Gap junctions (GJs) assembled from connexin (Cx) proteins allow direct cell–cell communication. While phosphorylation is known to regulate multiple GJ functions, much less is known about the role of ubiquitin in these processes. Using ubiquitylation-type-specific antibodies and Cx43 lysine-to-argini...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Kells-Andrews, Rachael M., Margraf, Rachel A., Fisher, Charles G., Falk, Matthias M.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104827/
https://ncbi.nlm.nih.gov/pubmed/30054380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.204321
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