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Degradation of connexins and gap junctions

Connexin proteins are short-lived within the cell, whether present in the secretory pathway or in gap junction plaques. Their levels can be modulated by their rate of degradation. Connexins, at different stages of assembly, are degraded through the proteasomal, endo-/lysosomal, and phago-/lysosomal...

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Autors principals: Falk, Matthias M., Kells, Rachael M., Berthoud, Viviana M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989500/
https://ncbi.nlm.nih.gov/pubmed/24486527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.01.031
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