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Phosphorylation regulates connexin43/ZO-1 binding and release, an important step in gap junction turnover

To investigate whether connexin phosphorylation regulates the known role of zonula occludens-1 protein (ZO-1) in gap junction (GJ) function, we generated and analyzed a series of phosphomimetic and phosphorylation-dead mutants by mutating known conserved regulatory serine (S) residues 255, 279/282,...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Thévenin, Anastasia F., Margraf, Rachel A., Fisher, Charles G., Kells-Andrews, Rachael M., Falk, Matthias M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706988/
https://ncbi.nlm.nih.gov/pubmed/29021339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-07-0496
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