Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

Characterizing polyclonal antibody responses via currently available methods is inherently complex and difficult. Mapping epitopes in an immune response is typically incomplete, which creates a barrier to fully understanding the humoral response to antigens and hinders rational vaccine design effort...

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Bibliographic Details
Published in:Immunity
Main Authors: Bianchi, Matteo, Turner, Hannah L., Nogal, Bartek, Cottrell, Christopher A., Oyen, David, Pauthner, Matthias, Bastidas, Raiza, Nedellec, Rebecca, McCoy, Laura E., Wilson, Ian A., Burton, Dennis R., Ward, Andrew B., Hangartner, Lars
Format: Artigo
Language:Inglês
Published: Cell Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104742/
https://ncbi.nlm.nih.gov/pubmed/30097292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.07.009
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