Quantitation of tadalafil in human plasma using a sensitive and rapid LC-MS/MS method for a bioequivalence study

A highly sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the determination of tadalafil (TAD) in human plasma. TAD and its deuterated internal standard (IS), tadalafil-d3, were extracted from 200 µL plasma using Phenomenex Strata-X-C 33 µ extraction cartr...

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Bibliographic Details
Published in:J Pharm Anal
Main Authors: Bhadoriya, Abhaysingh, Dasandi, Bhavesh, Parmar, Dharmesh, Shah, Priyanka A., Shrivastav, Pranav S.
Format: Artigo
Language:Inglês
Published: Xi'an Jiaotong University 2018
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Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104147/
https://ncbi.nlm.nih.gov/pubmed/30140492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2018.01.003
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