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Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNA(Cys) and elongation factor SelB

In many organisms, the UGA stop codon is recoded to insert selenocysteine (Sec) into proteins. Sec incorporation in bacteria is directed by an mRNA element, known as the Sec-insertion sequence (SECIS), located downstream of the Sec codon. Unlike other aminoacyl-tRNAs, Sec-tRNA(Sec) is delivered to t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:RNA Biol
Hauptverfasser: Vargas-Rodriguez, Oscar, Englert, Markus, Merkuryev, Anna, Mukai, Takahito, Söll, Dieter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103700/
https://ncbi.nlm.nih.gov/pubmed/29879865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1474074
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