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Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNA(Cys) and elongation factor SelB

In many organisms, the UGA stop codon is recoded to insert selenocysteine (Sec) into proteins. Sec incorporation in bacteria is directed by an mRNA element, known as the Sec-insertion sequence (SECIS), located downstream of the Sec codon. Unlike other aminoacyl-tRNAs, Sec-tRNA(Sec) is delivered to t...

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Bibliographic Details
Published in:RNA Biol
Main Authors: Vargas-Rodriguez, Oscar, Englert, Markus, Merkuryev, Anna, Mukai, Takahito, Söll, Dieter
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103700/
https://ncbi.nlm.nih.gov/pubmed/29879865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1474074
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