Inhibiting autophagy reduces retinal degeneration caused by protein misfolding

Mutations in the genes necessary for the structure and function of vertebrate photoreceptor cells are associated with multiple forms of inherited retinal degeneration. Mutations in the gene encoding RHO (rhodopsin) are a common cause of autosomal dominant retinitis pigmentosa (adRP), with the Pro23H...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Yao, Jingyu, Qiu, Yaoyan, Frontera, Eric, Jia, Lin, Khan, Naheed W., Klionsky, Daniel J., Ferguson, Thomas A., Thompson, Debra A., Zacks, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper - Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103695/
https://ncbi.nlm.nih.gov/pubmed/29940785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1463121
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