Inhibiting autophagy reduces retinal degeneration caused by protein misfolding

Mutations in the genes necessary for the structure and function of vertebrate photoreceptor cells are associated with multiple forms of inherited retinal degeneration. Mutations in the gene encoding RHO (rhodopsin) are a common cause of autosomal dominant retinitis pigmentosa (adRP), with the Pro23H...

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Vydáno v:Autophagy
Hlavní autoři: Yao, Jingyu, Qiu, Yaoyan, Frontera, Eric, Jia, Lin, Khan, Naheed W., Klionsky, Daniel J., Ferguson, Thomas A., Thompson, Debra A., Zacks, David N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Paper - Basic Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103695/
https://ncbi.nlm.nih.gov/pubmed/29940785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1463121
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