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Drugging tRNA aminoacylation
Inhibition of tRNA aminoacylation has proven to be an effective antimicrobial strategy, impeding an essential step of protein synthesis. Mupirocin, the well-known selective inhibitor of bacterial isoleucyl-tRNA synthetase, is one of three aminoacylation inhibitors now approved for human or animal us...
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| Publicado no: | RNA Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6103670/ https://ncbi.nlm.nih.gov/pubmed/29345185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1429879 |
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