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Transcription factor target site search and gene regulation in a background of unspecific binding sites

Response time and transcription level are vital parameters of gene regulation. They depend on how fast transcription factors (TFs) find and how efficient they occupy their specific target sites. It is well known that target site search is accelerated by TF binding to and sliding along unspecific DNA...

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Podrobná bibliografie
Vydáno v:J Theor Biol
Hlavní autoři: Hettich, J., Gebhardt, J.C.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103292/
https://ncbi.nlm.nih.gov/pubmed/29870697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2018.05.037
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