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Nucleosomal Context of Binding Sites Influences Transcription Factor Binding Affinity and Gene Regulation
Transcription factor (TF) binding to its DNA target site plays an essential role in gene regulation. The location, orientation and spacing of transcription factor binding sites (TFBSs) also affect regulatory function of the TF. However, how nucleosomal context of TFBSs influences TF binding and subs...
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Publicado no: | Genomics Proteomics Bioinformatics |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5054407/ https://ncbi.nlm.nih.gov/pubmed/20172488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1672-0229(08)60045-5 |
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