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Multiple transcription factor binding sites predict AID targeting in non-immunoglobulin genes
Aberrant targeting of the enzyme Activation Induced Cytidine Deaminase (AID) results in the accumulation of somatic mutations in approximately 25% of expressed genes in germinal center B cells. Observations in Ung(−/−) Msh2(−/−) mice suggest that many other genes efficiently repair AID-induced lesio...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689293/ https://ncbi.nlm.nih.gov/pubmed/23514741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202547 |
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