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Probing the chemical–biological relationship space with the Drug Target Explorer

Modern phenotypic high-throughput screens (HTS) present several challenges including identifying the target(s) that mediate the effect seen in the screen, characterizing ‘hits’ with a polypharmacologic target profile, and contextualizing screen data within the large space of drugs and screening mode...

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Bibliografiska uppgifter
I publikationen:J Cheminform
Huvudupphovsmän: Allaway, Robert J., La Rosa, Salvatore, Guinney, Justin, Gosline, Sara J. C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer International Publishing 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102167/
https://ncbi.nlm.nih.gov/pubmed/30128806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-018-0297-4
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