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Probing the chemical–biological relationship space with the Drug Target Explorer
Modern phenotypic high-throughput screens (HTS) present several challenges including identifying the target(s) that mediate the effect seen in the screen, characterizing ‘hits’ with a polypharmacologic target profile, and contextualizing screen data within the large space of drugs and screening mode...
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| Publicado no: | J Cheminform |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6102167/ https://ncbi.nlm.nih.gov/pubmed/30128806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-018-0297-4 |
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