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Analysis of Beta-cell Function Using Single-cell Resolution Calcium Imaging in Zebrafish Islets

Pancreatic beta-cells respond to increasing blood glucose concentrations by secreting the hormone insulin. The dysfunction of beta-cells leads to hyperglycemia and severe, life-threatening consequences. Understanding how the beta-cells operate under physiological conditions and what genetic and envi...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Janjuha, Sharan, Pal Singh, Sumeet, Ninov, Nikolay
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102039/
https://ncbi.nlm.nih.gov/pubmed/30035763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57851
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