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Evaluation of the Impact of Protein Aggregation on Cellular Oxidative Stress in Yeast

Protein misfolding and aggregation into amyloid conformations have been related to the onset and progression of several neurodegenerative diseases. However, there is still little information about how insoluble protein aggregates exert their toxic effects in vivo. Simple prokaryotic and eukaryotic m...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Carija, Anita, Ventura, Salvador, Navarro, Susanna
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101985/
https://ncbi.nlm.nih.gov/pubmed/29985335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57470
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