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Evaluation of the Impact of Protein Aggregation on Cellular Oxidative Stress in Yeast

Protein misfolding and aggregation into amyloid conformations have been related to the onset and progression of several neurodegenerative diseases. However, there is still little information about how insoluble protein aggregates exert their toxic effects in vivo. Simple prokaryotic and eukaryotic m...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: Carija, Anita, Ventura, Salvador, Navarro, Susanna
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101985/
https://ncbi.nlm.nih.gov/pubmed/29985335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57470
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