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Evaluation of the Impact of Protein Aggregation on Cellular Oxidative Stress in Yeast

Protein misfolding and aggregation into amyloid conformations have been related to the onset and progression of several neurodegenerative diseases. However, there is still little information about how insoluble protein aggregates exert their toxic effects in vivo. Simple prokaryotic and eukaryotic m...

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Vydáno v:J Vis Exp
Hlavní autoři: Carija, Anita, Ventura, Salvador, Navarro, Susanna
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101985/
https://ncbi.nlm.nih.gov/pubmed/29985335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57470
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