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The Role of Autophagy in the Degradation of Misfolded HLA-B27 Heavy Chains

OBJECTIVE. To determine whether autophagy is involved in the degradation of misfolded HLA-B27 in experimental spondyloarthritis. METHODS. Bone marrow derived macrophages from HLA-B27 and human β(2)m (hβ(2)m) transgenic rats were examined with and without IFNγ and proteasome or autophagy inhibitors....

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Bibliografiska uppgifter
I publikationen:Arthritis Rheumatol
Huvudupphovsmän: Navid, Fatemeh, Layh-Schmitt, Gerlinde, Sikora, Keith A., Cougnoux, Antony, Colbert, Robert A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101661/
https://ncbi.nlm.nih.gov/pubmed/29342507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40414
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