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The Role of Autophagy in the Degradation of Misfolded HLA-B27 Heavy Chains
OBJECTIVE. To determine whether autophagy is involved in the degradation of misfolded HLA-B27 in experimental spondyloarthritis. METHODS. Bone marrow derived macrophages from HLA-B27 and human β(2)m (hβ(2)m) transgenic rats were examined with and without IFNγ and proteasome or autophagy inhibitors....
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| Publicado no: | Arthritis Rheumatol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6101661/ https://ncbi.nlm.nih.gov/pubmed/29342507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40414 |
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