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HLA-B27 Alters the Response to TNFα and Promotes Osteoclastogenesis in Bone Marrow Monocytes from HLA-B27 Transgenic Rats

OBJECTIVE: To determine whether HLA-B27 expression alters the response of bone marrow monocytes (BMMo) from HLA-B27/human β(2)-microglobulin transgenic (B27-Tg) rats to tumor necrosis factor-α (TNFα), and whether this affects cells involved in bone homeostasis. METHODS: BMMo were treated with recept...

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Detalhes bibliográficos
Main Authors: Layh-Schmitt, Gerlinde, Yang, Eva Y., Kwon, Grace, Colbert, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857096/
https://ncbi.nlm.nih.gov/pubmed/23666508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38001
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