Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

The repair of double-stranded breaks (DSBs) in DNA is a highly coordinated process, necessitating the formation and resolution of multi-protein repair complexes. This process is regulated by a myriad of proteins that promote the association and disassociation of proteins to these lesions. Thanks in...

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Vydáno v:J Vis Exp
Hlavní autoři: Murthy, Vaibhav, Dacus, Dalton, Gamez, Monica, Hu, Changkun, Wendel, Sebastian O., Snow, Jazmine, Kahn, Andrew, Walterhouse, Stephen H., Wallace, Nicholas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2018
Témata:
Cancer Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101641/
https://ncbi.nlm.nih.gov/pubmed/29939192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57653
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