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Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

The repair of double-stranded breaks (DSBs) in DNA is a highly coordinated process, necessitating the formation and resolution of multi-protein repair complexes. This process is regulated by a myriad of proteins that promote the association and disassociation of proteins to these lesions. Thanks in...

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Bibliografske podrobnosti
izdano v:J Vis Exp
Main Authors: Murthy, Vaibhav, Dacus, Dalton, Gamez, Monica, Hu, Changkun, Wendel, Sebastian O., Snow, Jazmine, Kahn, Andrew, Walterhouse, Stephen H., Wallace, Nicholas A.
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101641/
https://ncbi.nlm.nih.gov/pubmed/29939192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57653
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