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Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines
Multiple enhancers often regulate a given gene, yet for most genes, it remains unclear which enhancers are necessary for gene expression, and how these enhancers combine to produce a transcriptional response. As millions of enhancers have been identified, high-throughput tools are needed to determin...
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| Publicado no: | J Vis Exp |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6101477/ https://ncbi.nlm.nih.gov/pubmed/29912188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57883 |
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