Transplantation from a symptomatic carrier sister restores host defenses but does not prevent colitis in NEMO deficiency

NF-κB essential modulator (NEMO) deficiency causes ectodermal dysplasia with immunodeficiency in males, while manifesting as incontinentia pigmenti in heterozygous females. We report a family with NEMO deficiency, in which a female carrier displayed skewed X-inactivation favoring the mutant NEMO all...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Immunol
Main Authors: Klemann, Christian, Pannicke, Ulrich, Morris-Rosendahl, Deborah J., Vlantis, Katerina, Rizzi, Marta, Uhlig, Holm, Vraetz, Thomas, Speckmann, Carsten, Strahm, Brigitte, Pasparakis, Manolis, Schwarz, Klaus, Ehl, Stephan, Rohr, Jan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101191/
https://ncbi.nlm.nih.gov/pubmed/26812624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2016.01.010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados