Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on β-Amyloid Aggregation and Neurotoxicity

Despite the controversial outcomes of clinical trials executed so far, the prevention of β-amyloid (Aβ) deposition and neurotoxicity by small molecule inhibitors of Aβ aggregation remains a target intensively pursued in the search of effective drugs for treating Alzheimer’s disease (AD) and related...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Molecules
Huvudupphovsmän: Purgatorio, Rosa, de Candia, Modesto, De Palma, Annalisa, De Santis, Francesco, Pisani, Leonardo, Campagna, Francesco, Cellamare, Saverio, Altomare, Cosimo Damiano, Catto, Marco
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100259/
https://ncbi.nlm.nih.gov/pubmed/29949947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23071544
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk