Chasing ChEs-MAO B Multi-Targeting 4-Aminomethyl-7-Benzyloxy-2H-Chromen-2-ones

A series of 4-aminomethyl-7-benzyloxy-2H-chromen-2-ones was investigated with the aim of identifying multiple inhibitors of cholinesterases (acetyl- and butyryl-, AChE and BChE) and monoamine oxidase B (MAO B) as potential anti-Alzheimer molecules. Starting from a previously reported potent MAO B in...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Rullo, Mariagrazia, Catto, Marco, Carrieri, Antonio, de Candia, Modesto, Altomare, Cosimo Damiano, Pisani, Leonardo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943664/
https://ncbi.nlm.nih.gov/pubmed/31835376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24244507
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