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Backbone-free duplex-stacked monomer nucleic acids exhibiting Watson–Crick selectivity

We demonstrate that nucleic acid (NA) mononucleotide triphosphates (dNTPs and rNTPs), at sufficiently high concentration and low temperature in aqueous solution, can exhibit a phase transition in which chromonic columnar liquid crystal ordering spontaneously appears. Remarkably, this polymer-free st...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Smith, Gregory P., Fraccia, Tommaso P., Todisco, Marco, Zanchetta, Giuliano, Zhu, Chenhui, Hayden, Emily, Bellini, Tommaso, Clark, Noel A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099888/
https://ncbi.nlm.nih.gov/pubmed/29967169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721369115
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