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Adeno-Associated Virus–Mediated Gene Transfer of Tissue Inhibitor of Metalloproteinases-1 Impairs Neutrophil Extracellular Trap Formation and Ameliorates Hepatic Ischemia and Reperfusion Injury

Matrix metalloproteinase-9 (MMP-9) is abundantly expressed by infiltrating leukocytes and contributes to the pathogenesis of hepatic ischemia and reperfusion injury (IRI). On the other hand, its physiological inhibitor, the tissue inhibitor of metalloproteinases-1 (TIMP-1), is available in insuffici...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Am J Pathol
मुख्य लेखकों: Duarte, Sergio, Matian, Patrick, Ma, Stacy, Busuttil, Ronald W., Coito, Ana J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Investigative Pathology 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099362/
https://ncbi.nlm.nih.gov/pubmed/29870740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.05.002
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