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Late‐Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO(2)
A robust, click‐chemistry‐inspired procedure for radiolabeling of cyclic ureas was developed. This protocol, suitable for all carbon isotopes ((11)C, (13)C, (14)C), is based on the direct functionalization of carbon dioxide: the universal building block for carbon radiolabeling. The strategy is oper...
שמור ב:
| הוצא לאור ב: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
John Wiley and Sons Inc.
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6099343/ https://ncbi.nlm.nih.gov/pubmed/29862657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201804838 |
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