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Genome Wide Distribution of Linker Histone H1.0 is Independent of MeCP2
Previous studies suggested that MeCP2 competes with linker histone H1, but this hypothesis has never been tested in vivo. Here, we performed ChIP-Seq of Flag-tagged-H1.0 in mouse forebrain excitatory neurons. Unexpectedly, Flag-H1.0 and MeCP2 occupied similar genomic regions and the Flag-H1.0 bindin...
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| Publicado no: | Nat Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6099063/ https://ncbi.nlm.nih.gov/pubmed/29802390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0155-8 |
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