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Design, synthesis and activity of light deactivatable microRNA inhibitor

miRNAs are key cellular regulators and their dysregulation is associated with many human diseases. They are usually produced locally in a spatiotemporally controlled manner to target mRNAs and regulate gene expression. Thus, developing chemical tools for manipulating miRNA with spatiotemporal precis...

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Detalhes bibliográficos
Publicado no:Bioorg Chem
Main Authors: Yan, Hao, Bhattarai, Umesh, Song, Yabin, Liang, Fu-Sen
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098719/
https://ncbi.nlm.nih.gov/pubmed/29990897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2018.07.003
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