ΔNp63γ/SRC/Slug signalling axis promotes epithelial-to-mesenchymal transition in squamous cancers

PURPOSE: To investigate the regulation of epithelial-to-mesenchymal transition (EMT) in Head and Neck Squamous Cell Carcinoma (HNSCC) and its importance in tumour invasion. EXPERIMENTAL DESIGN: We use a 3D invasive organotypic raft culture model of human foreskin keratinocytes expressing the E6/E7 g...

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Pubblicato in:Clin Cancer Res
Autori principali: Srivastava, Kirtiman, Pickard, Adam, Craig, Stephanie G, Quinn, Gerard P, Lambe, Shauna M, James, Jacqueline A, McDade, Simon S, McCance, Dennis J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098695/
https://ncbi.nlm.nih.gov/pubmed/29739791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-3775
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