ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion

Tumor invasion can be induced by changes in gene expression that alter cell phenotype. The transcription factor ΔNp63α promotes basal-like breast cancer (BLBC) migration by inducing the expression of the mesenchymal genes Slug and Axl, which confers cells with a hybrid epithelial/mesenchymal state....

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Udgivet i:Oncotarget
Main Authors: Dang, Tuyen T., Westcott, Jill M., Maine, Erin A., Kanchwala, Mohammed, Xing, Chao, Pearson, Gray W.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053748/
https://ncbi.nlm.nih.gov/pubmed/27081041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8696
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