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ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion

Tumor invasion can be induced by changes in gene expression that alter cell phenotype. The transcription factor ΔNp63α promotes basal-like breast cancer (BLBC) migration by inducing the expression of the mesenchymal genes Slug and Axl, which confers cells with a hybrid epithelial/mesenchymal state....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dang, Tuyen T., Westcott, Jill M., Maine, Erin A., Kanchwala, Mohammed, Xing, Chao, Pearson, Gray W.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053748/
https://ncbi.nlm.nih.gov/pubmed/27081041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8696
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