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UBXD1 is a mitochondrial recruitment factor for p97/VCP and promotes mitophagy
Clearance of damaged mitochondria through mitophagy is critical for maintaining mitochondrial fidelity and the prevention of neurodegeneration. Here, we report on the UBX domain-containing, p97/VCP cofactor UBXD1/UBXN6/UBXDC2 and its role in mitophagy. Recognizing depolarized mitochondria via its C-...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6098094/ https://ncbi.nlm.nih.gov/pubmed/30120381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30963-z |
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