Laddar...

UBXD1 is a mitochondrial recruitment factor for p97/VCP and promotes mitophagy

Clearance of damaged mitochondria through mitophagy is critical for maintaining mitochondrial fidelity and the prevention of neurodegeneration. Here, we report on the UBX domain-containing, p97/VCP cofactor UBXD1/UBXN6/UBXDC2 and its role in mitophagy. Recognizing depolarized mitochondria via its C-...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Bento, Ana C., Bippes, Claudia C., Kohler, Corina, Hemion, Charles, Frank, Stephan, Neutzner, Albert
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098094/
https://ncbi.nlm.nih.gov/pubmed/30120381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30963-z
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!