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Convergent Use of Heptacoordination for Cation Selectivity by RNA and Protein Metalloregulators

The large yybP-ykoY family of bacterial riboswitches is broadly distributed phylogenetically. Previously, these gene-regulatory RNAs were proposed to respond to Mn(2+). X-ray crystallography revealed a binuclear cation-binding pocket. This comprises one hexacoordinate site, with six oxygen ligands,...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Bachas, Sharrol T., Ferré-D’Amaré, Adrian R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097924/
https://ncbi.nlm.nih.gov/pubmed/29805037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.04.016
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