A novel recombinant human plasminogen activator: Efficient expression and hereditary stability in transgenic goats and in vitro thrombolytic bioactivity in the milk of transgenic goats

BACKGROUND: Thromboses is a rapidly growing medical problem worldwide. Low-cost, high-scale production of thrombotic drugs is needed to meet the demand. The production of biomolecules in transgenic animals might help address this issue. To our knowledge, the expression of recombinant human plasminog...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: He, Zhengyi, Lu, Rui, Zhang, Ting, Jiang, Lei, Zhou, Minya, Wu, Daijin, Cheng, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097695/
https://ncbi.nlm.nih.gov/pubmed/30118482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201788
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