Accurately cleavable goat β-lactoglobulin signal peptide efficiently guided translation of a recombinant human plasminogen activator in transgenic rabbit mammary gland

Poor expression is the key factor hampering the large-scale application of transgenic animal mammary gland bioreactors. A very different approach would be to evaluate the secretion of recombinant proteins into milk in response to a cleavable signal peptide of highly secreted lactoproteins. We previo...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Lu, Rui, Zhang, Ting, Song, Shaozheng, Zhou, Minya, Jiang, Lei, He, Zhengyi, Yuan, Yuguo, Yuan, Tingting, Lu, Yaoyao, Yan, Kunning, Cheng, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597847/
https://ncbi.nlm.nih.gov/pubmed/31196965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190596
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